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Zoloft is FDA approved to treat depression, certain types of social anxiety conditions, posttraumatic stress disorder (PTSD), panic disorder, obsessive-compulsive disorder (OCD), and premenstrual dysphoric disorder (PMDD) in adults over age 18. It is also approved for OCD in children and adolescents age 6-17 years.

Effexor was approved for the treatment of depression in 1993. Effexor increases the levels of both serotonin and norepinephrine (two neurotransmitters though to cause the symptoms of depression) in the brain.

Paxil is a selective serotonin reuptake inhibitor (SSRI) approved for treatment of depression and several related disorders in adults. Paxil is not approved by the FDA (Food and Drug Administration) for treatment of children, because studies presented to the FDA have not shown that Paxil is effective for treating children under 18. Wellbutrin is used to treat major depressive disorder and seasonal affective disorder. At least one brand of bupropion (Zyban) is used to help people stop smoking by reducing cravings and other withdrawal effects.